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← Xaira Therapeutics

Senior Software Engineer, X-Scientist

Xaira Therapeutics
Location
South San Francisco, California, United States
Posted
2 months ago
Department
Computational Protein Design
Salary
$189,000 - $245,000
What they actually want (must-haves)
  • Strong Python engineering fundamentals with clean, typed, tested, maintainable code
  • Experience building at least one of the following: a production library, CLI, API, SDK, backend service, workflow system, or developer platform
  • Familiarity with LLM application development, agent frameworks, tool calling, MCP-style interfaces, or orchestration systems
  • Comfort working with complex systems that combine multiple components, external calls, domain-specific logic, and evolving user needs
  • Good instincts for abstraction, error handling, reliability, and designing software that can grow across use cases
  • Strong communication skills and ability to work in a collaborative, multidisciplinary environment
Nice to have
  • Background or interest in computational biology, bioinformatics, protein design, single-cell genomics, biomedical AI, or adjacent domains
  • Familiarity with biomedical databases or tools such as PubMed, UniProt, AlphaFold, PDB, DepMap, or related resources
  • Curiosity about biology and scientific research; you do not need a biology background, but you should be excited to learn the domain and work closely with scientists and ML researchers
What the job really is

As a Senior Software Engineer on the X-Scientist team at Xaira Therapeutics, you will develop backend systems and APIs that integrate AI models with scientific tools and workflows. Your work will involve creating tool-calling infrastructure, SDKs, and interfaces that facilitate scientific analyses, while ensuring reliability and maintainability of long-running workflows. Collaboration with multidisciplinary teams will be essential to transform complex research workflows into user-friendly software solutions.

Benefits
  • Competitive compensation and benefits package
  • Base salary range of $205,000 - $275,000 annually
  • Total cash compensation up to $235,000 - $325,000
  • Open, flexible, and friendly work environment
  • Platform for developing long-term careers
Things to weigh
  • No specific technologies or frameworks mentioned, which may affect the clarity of the tech stack
  • The role involves collaboration with scientists and ML researchers, which may require a steep learning curve for those without a biology background
Job score3.4/5
Benefits3/5
Freshness1/5
Career value4/5
Role clarity4/5
Pay transparency5/5

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