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← Veracyte

Principal Bioinformatics Scientist

Veracyte
Location
San Diego, California, United States; South San Francisco, California, United States
Posted
19 days ago
Department
330 Bioinformatics & Data Science
Salary
$184,000 - $204,000
What they actually want (must-haves)
  • Ph.D. in Bioinformatics, Computational Biology, Genomics, Biostatistics, or a closely related quantitative field
  • Minimum 8 years of total relevant experience, with at least 5 years of direct industry experience in biotech, diagnostics, or regulated healthcare environments
  • Demonstrated experience leading NGS‑based assay development for clinical diagnostics
  • Hands-on experience with ctDNA-based MRD assays, including personalized or tumor-informed approaches
  • Strong programming skills in Python, with experience developing reproducible, production‑grade analysis pipelines
  • Proven experience working in design‑controlled, regulated environments (CAP/CLIA LDT, IVD, or equivalent)
Nice to have
  • 1-2 years management experience preferred
  • Experience developing and deploying bioinformatics workflows in AWS
  • Strong understanding of germline and somatic mutation processes leading to complex variation and genome-wide biomarkers with potential clinical utility
  • Working knowledge of R
  • Experience with relational and non-relational database technologies is a plus
What the job really is

The Principal Bioinformatics Scientist at Veracyte will lead the bioinformatics strategy for the development of next-generation minimal residual disease (MRD) laboratory-developed tests (LDTs). This role involves driving assay concepts, analytical development, and validation while collaborating with various teams to deliver clinically actionable diagnostics. The position requires deep expertise in NGS-based oncology assays and ctDNA biology, with responsibilities spanning from study design to regulatory compliance and mentorship of junior scientists.

Benefits
  • Competitive compensation
  • Discretionary bonuses/incentives
  • Restricted stock units
  • Commitment to fostering an inclusive workforce
Things to weigh
  • Salary range is location-dependent, with specific figures provided for San Diego and South San Francisco offices
  • No specific mention of remote work policies beyond hybrid options
  • Role involves significant cross-functional collaboration, which may impact work style and pace
Job score4.2/5
Benefits2/5
Freshness4/5
Career value5/5
Role clarity5/5
Pay transparency5/5

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