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← Twist Bioscience

Senior Computational Scientist

Twist Bioscience
Location
USA - South San Francisco, CA
Posted
18 days ago
Department
Research & Development
What they actually want (must-haves)
  • Minimum of 5 years of industry experience with a PhD
  • PhD in computational biology, bioinformatics, machine learning, computer science, protein science, or a related field
  • Extensive experience developing algorithms for protein design, engineering, discovery, or sequence analysis
  • Demonstrated experience developing and applying AI/ML methods to proteins or other biological sequences
  • Strong understanding of protein language models (PLMs) and protein sequence-structure-function relationships
  • Experience analyzing NGS data from biological selection, screening, or related workflows
Nice to have
  • Experience with antibody discovery, engineering, or characterization
  • Experience with biopanning, display-based discovery, or other protein-selection platforms
  • Experience integrating protein sequence, NGS, and experimental assay data
  • Experience with generative protein design, property prediction, or candidate-ranking methods
What the job really is

The Senior Computational Scientist role at Twist involves developing AI and computational solutions for protein design and discovery. You will collaborate with various teams to create algorithms that integrate protein sequences with experimental data, lead the development of AI methods, and translate scientific needs into practical solutions. This position requires hands-on experience in computational biology and machine learning, particularly with protein language models.

Benefits
  • Eligible for bonus
  • Equity
  • Generous benefits package
Things to weigh
  • No specific details on the benefits package provided
  • Base salary range provided is specific to the San Francisco Bay Area and may vary by location
  • Role involves a mix of research, software development, and troubleshooting, which may require flexibility
Job score3.2/5
Benefits2/5
Freshness4/5
Career value5/5
Role clarity5/5
Pay transparency0/5

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