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← Spyre Therapeutics

Vice President, Clinical Development

Spyre Therapeutics
Location
US- Remote
Posted
2 months ago
Department
Clinical Development
Salary
$366,000 to $398,000
What they actually want (must-haves)
  • MD or equivalent medical degree
  • Minimum of 7+ years clinical development experience within the pharmaceutical or biotech industry
  • Substantial leadership experience in immunology, inflammation, or gastroenterology
  • Demonstrated success leading mid- and late-stage clinical development programs
  • Strong understanding of clinical trial design, biostatistics, translational medicine, drug development, and global regulatory requirements
  • Demonstrated ability to influence strategy and drive cross-functional decision-making in a matrixed environment
Nice to have
  • Training and/or experience in clinical development in gastroenterology or immunology & inflammation
  • Experience developing antibody therapeutics
  • Experience leading complex, adaptive, umbrella, basket, or platform clinical trials
  • Deep expertise in inflammatory bowel disease and/or other immune-mediated inflammatory disorders
  • Significant experience with global regulatory interactions and submissions, including INDs, CTAs, briefing documents for global regulatory agencies
What the job really is

The Vice President of Clinical Development at Spyre Therapeutics will lead the clinical strategy and execution for antibody therapeutics targeting inflammatory bowel disease (IBD). This role involves hands-on leadership in ongoing clinical trials, protocol development, and collaboration with cross-functional teams to ensure successful study execution and regulatory compliance. The ideal candidate will balance strategic oversight with direct involvement in clinical operations, contributing to the company's growth in a fast-paced biotech environment.

Benefits
  • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
  • Unlimited PTO
  • Two, one-week company-wide shutdowns each year
  • Commitment to provide professional development opportunities
  • Remote working environment with frequent in-person meetings
Things to weigh
  • No specific details on the company's current pipeline or stage of development for the therapies mentioned
  • The role requires balancing strategic leadership with hands-on execution, which may be demanding in a high-growth environment
  • The expected salary range is provided, but actual pay may vary based on various factors
Job score3.8/5
Benefits3/5
Freshness1/5
Career value5/5
Role clarity5/5
Pay transparency5/5

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