HHiring Reality
← Spyre Therapeutics

Senior Director, Biostatistics

Spyre Therapeutics
Location
US- Remote
Posted
2 months ago
Department
Biometrics
Salary
$ 275,000 to $290,000
What they actually want (must-haves)
  • PhD Degree in Biostatistics, Statistics, or a related field
  • 10-12 years of experience in biostatistics within the pharmaceutical, biotech, or CRO industry
  • Strong knowledge of statistical methodologies and their application in clinical trials
  • Experience with regulatory submissions and interactions with regulatory agencies
  • Proficiency in statistical software (e.g., SAS, R) and data management systems
  • Experience with CDSIC including SDTM, ADaM, CDASH
Nice to have
  • Working knowledge of Bayesian methodology
  • Successful track record of working independently in a matrixed organization
What the job really is

The Senior Director of Biostatistics will lead the biometrics team and provide strategic input for clinical development programs. Responsibilities include overseeing statistical activities for clinical trials, collaborating with cross-functional teams, managing biometrics vendors, and interacting with global health authorities. This role requires hands-on involvement in trial design, statistical analysis, and ensuring high-quality data management.

Benefits
  • Market competitive compensation and benefits package
  • Base salary, performance bonus, equity grant opportunities
  • Health, welfare & retirement benefits
  • Unlimited PTO
  • Two, one-week company-wide shutdowns each year
  • Commitment to provide professional development opportunities
Things to weigh
  • The expected salary range is provided, but actual pay may vary based on various factors
  • The role involves frequent in-person meetings despite being remote
  • The company is still young and shaping its culture, which may appeal to some candidates but could be a challenge for others
Job score3.8/5
Benefits4/5
Freshness1/5
Career value4/5
Role clarity5/5
Pay transparency5/5

Applying to Spyre Therapeutics?

See how your résumé matches this role — and tailor it from what actually gets interviews.