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Senior Scientist I/Senior Scientist II, Analytical Sciences

Sail Biomedicines
Location
Cambridge, MA
Posted
2 days ago
Department
Sail - Technical Development & Operations
Salary
$125,000 - $175,000
What they actually want (must-haves)
  • Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field with 3+ years of relevant industry experience; M.S. with 7+ years of relevant industry experience; or B.S. with 9+ years of relevant industry experience
  • Demonstrated experience developing, optimizing, qualifying, validating, and transferring analytical methods in a biotechnology or pharmaceutical environment
  • Strong scientific background in analytical development for biologics, nucleic acid therapeutics, lipid nanoparticles, gene therapies, or other complex therapeutic modalities
  • Hands-on experience with multiple analytical techniques, such as chromatography, capillary electrophoresis, UV-Vis spectroscopy, dynamic light scattering, plate-based assays, ligand-binding assays, molecular biology methods, or cell-based assays
  • Demonstrated ability to independently design experiments, analyze complex data, troubleshoot technical problems, and drive studies to completion
  • Experience supporting product characterization, process development, formulation development, stability studies, specifications, or comparability assessments
Nice to have
  • Experience with RNA analytical characterization, including methods for RNA identity, integrity, purity, concentration, structure, and functional expression
  • Experience with lipid nanoparticle characterization methods, such as particle size, polydispersity, encapsulation efficiency, lipid content, or potency
  • Experience supporting GLP toxicology, clinical manufacturing, stability, or regulatory submission activities, particularly experience with early Phase programs
  • Working knowledge of phase-appropriate GxP requirements and relevant ICH guidance
  • Experience working with CDMOs or contract testing laboratories
What the job really is

The Senior Scientist I/II in Analytical Sciences at Sail Biomedicines will lead the development and optimization of analytical methods for RNA and lipid nanoparticle programs. This role involves troubleshooting complex analytical challenges, collaborating with cross-functional teams, and ensuring high-quality data generation to support preclinical and clinical advancements. The successful candidate will also mentor junior scientists and stay updated on scientific literature and regulatory guidance.

Things to weigh
  • Salary range provided is $125,000 - $175,000
  • Role requires strong technical leadership and the ability to operate in a dynamic, fast-paced environment
  • No specific benefits or perks mentioned in the posting
Job score4/5
Benefits1/5
Freshness5/5
Career value4/5
Role clarity5/5
Pay transparency5/5

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