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← Profluent

Lead Scientist / Associate Director, Bioinformatics and Data Science

Profluent
Location
Emeryville, California, United States; Hybrid (2-3 days on-site)
Posted
2 months ago
Department
Bioinformatics
What they actually want (must-haves)
  • PhD or MS in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field
  • PhD with 5+ years or MS with 7+ years of industry experience applying NGS and computational analysis to gene or cell therapy development
  • Deep expertise in the design, analysis, and interpretation of high-throughput sequencing assays
  • Strong programming and quantitative analysis skills, particularly in Python
  • Proven ability to translate complex sequencing data into clear biological insights and program decisions
  • Experience partnering closely with experimental scientists to guide assay design, troubleshoot results, and define follow-up studies
Nice to have
  • Experience with CRISPR-based gene editing data and analysis
  • Familiarity with SQL and data modeling for biological or experimental data
  • Experience with LIMS platforms (e.g., Benchling) and lab data integration
  • Track record of developing production-quality scientific software and tools
What the job really is

In this role, you will lead the development and operation of Profluent's NGS analysis platform, focusing on gene editing, protein design, and therapeutic programs. You will collaborate with wet-lab teams, establish rigorous practices in bioinformatics, and mentor a growing team. Your work will involve translating large-scale sequencing data into actionable biological insights and ensuring the scalability and reproducibility of computational workflows.

Benefits
  • High-growth opportunity with meaningful impact on the future of protein design
  • Competitive compensation package with equity participation
  • 401(k) with a strong employer match
  • Comprehensive benefits including health/dental/vision insurance
  • Generous PTO policy and commitment to work-life balance
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology
Things to weigh
  • No remote work option mentioned, as the role requires 2-3 days on-site
  • Work authorization in the U.S. is required without employer sponsorship
  • The salary range is provided, which may help in evaluating the compensation package
Job score2.8/5
Benefits3/5
Freshness1/5
Career value5/5
Role clarity5/5
Pay transparency0/5

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