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In Vivo Study Specialist

Parabilis Medicines
Location
Cambridge
Posted
25 days ago
Department
Biology
Salary
$75,000-$85,000
What they actually want (must-haves)
  • Extensive hands-on experience with mouse oncology models, including human xenograft, syngeneic, PDX, and genetically engineered mouse models.
  • Demonstrated mastery of advanced in vivo techniques: IV, IP, SC, and PO dosing; serial blood collection and PK sampling; tumor measurement; necropsy; and multi-tissue harvest.
  • Strong, hands-on experience with ex vivo tissue processing and assay preparation, histology sample prep, and molecular sample extraction (RNA/DNA/protein).
  • Experience with pharmacology, PK/PD, and efficacy study execution and analysis.
  • BS in Biology, Pharmacology, Cancer Biology, Immunology, or a related scientific discipline, or AALAS certification with equivalent relevant industry experience, and 3–5+ years of experience in biotechnology or pharmaceutical research.
  • Strong understanding of animal welfare regulations and experience supporting IACUC protocols.
Nice to have
  • Experience performing minor and major rodent surgical procedures, including oncology-specific survival surgeries.
  • Familiarity with histology/IHC, and molecular biology techniques (qPCR, Western Blot, ELISA).
  • Exposure to translational pharmacology and oncology drug discovery programs.
  • Experience working in a fast-paced, cross-functional biotechnology environment.
What the job really is

The In Vivo Study Specialist will be responsible for executing in vivo pharmacology studies in mouse oncology models and preparing ex vivo assays from tumor and normal tissues for molecular and immune analysis. This hands-on laboratory role involves collaborating with various teams to generate preclinical data that advances Helicon peptide therapeutics toward clinical development, while also maintaining detailed experimental documentation and contributing to study reports.

Benefits
  • Base salary range of $75,000-$85,000, depending on experience and qualifications.
  • Annual target bonus.
  • Equity.
  • Comprehensive suite of competitive benefits designed to support overall well-being.
Things to weigh
  • Base salary range provided, but may not be competitive depending on market standards.
  • Role heavily focused on in vivo studies, which may limit exposure to other areas of drug discovery.
  • The position requires a strong technical skill set, which may not appeal to those looking for a more strategic or managerial role.
Job score4/5
Benefits2/5
Freshness4/5
Career value4/5
Role clarity5/5
Pay transparency5/5

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