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← Manifold AI

Staff Software Engineer | Core Platform

Manifold AI
Location
Cambridge, MA
Posted
12 days ago
Department
Engineering
Salary
$170,000–$220,000
What they actually want (must-haves)
  • 8+ years of enterprise software experience, particularly in backend, infrastructure-adjacent, or distributed systems work
  • Mastery of Python and deep infrastructure-as-code experience with Terraform
  • Experience managing compute environments on AWS including autoscaling and cost/performance tradeoffs
  • Operational ownership mindset with a focus on observability and production outcomes
  • Experience integrating AI tools into engineering workflows
  • Strong understanding of the life sciences mission and its importance
Nice to have
  • Bioinformatics workflow experience (WDL, Nextflow, or Cromwell)
  • General life sciences or regulated-industry experience
What the job really is

As a Staff Software Engineer on the Core Platform team at Manifold, you will design and operate compute infrastructure and workflow orchestration services that support enterprise users in analyzing genomics and life sciences datasets. This hands-on role involves mentoring engineers, improving service reliability, and translating customer requirements into platform capabilities, all while contributing to the company's AI-native vision in life sciences.

Benefits
  • Strong compensation packages
  • Excellent benefits
Things to weigh
  • Salary range provided is $170,000–$220,000, but final offers may vary based on experience
  • Role involves significant responsibility and ownership, which may not suit all candidates
  • The position requires a proactive approach to operational standards and reliability
Job score3.8/5
Benefits1/5
Freshness5/5
Career value4/5
Role clarity4/5
Pay transparency5/5

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