HHiring Reality
← Legend Biotech US

Sr. Scientist, Lentivirus Upstream Processing

Legend Biotech US
Location
Somerset, New Jersey, United States
Posted
19 days ago
Department
Process Analytical Development
What they actually want (must-haves)
  • Advanced degree (PhD preferred, or MS) in Chemical Engineering, Bioengineering, or a related field
  • 5-8 years (PhD) or 8+ years (MS) of experience in process development or manufacturing within a biotech or pharmaceutical setting
  • Hands-on experience in mammalian cell culture (HEK293, HEK293T), seed train expansion, feeding strategy, and transient transfection optimization specifically for viral vectors (Lentivirus preferred)
  • Demonstrated proficiency in developing and implementing bioreactor scale-up and scale-down models
  • Solid understanding of GMP manufacturing requirements and CMC strategies for early-phase clinical trials
  • Direct experience with cell and lentiviral vector technologies within the current emerging field
Nice to have
  • Preferred experience in handling large-scale (>50L, e.g., 200L/500L) upstream bioreactor processes
  • Language(s): Mandarin is a plus
What the job really is

The Sr. Scientist, Lentivirus Upstream Processing will be a key contributor in the Technical Development team, focusing on designing and optimizing upstream production processes for lentiviral vectors. Daily responsibilities include executing experimental strategies, supporting GMP manufacturing, collaborating with cross-functional teams, and providing technical guidance to junior staff. The role emphasizes hands-on technical expertise in mammalian cell culture and bioprocess optimization to ensure high-quality vector products for advanced cell therapy programs.

Benefits
  • Medical, dental, and vision insurance
  • 401(k) retirement plan with a company match that vests fully on day one
  • Eight (8) weeks of paid parental leave after just three (3) months of employment
  • Paid time off policy including vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays
  • Flexible spending and health savings accounts
  • Life and AD&D insurance
Things to weigh
  • No salary listed, but a pay range is provided: $127,313 — $167,099 USD
  • The role requires a significant amount of hands-on technical expertise, which may not appeal to candidates seeking more strategic or managerial positions.
  • The position is focused on compliance with GMP and regulatory requirements, which may involve a rigorous work environment.
Job score3.6/5
Benefits5/5
Freshness4/5
Career value4/5
Role clarity5/5
Pay transparency0/5

Applying to Legend Biotech US?

See how your résumé matches this role — and tailor it from what actually gets interviews.