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Associate Director, Analytical Development

Kymera Therapeutics
Location
Watertown, MA
Posted
1 month ago
Department
Technical Operations & Quality
Salary
$160,000 – $240,000
What they actually want (must-haves)
  • PhD in Analytical Chemistry or related life sciences field preferred, but not required
  • 10+ years of experience in CMC analytical development of small molecule drug substance and oral solid dosage forms
  • Experience in developing impurity control strategies, including potentially mutagenic impurities (PMIs) and nitrosamine impurities
  • In-depth expertise in late phase test method development, method validation/transfer, and characterization of small-molecule drugs
  • Broad analytics expertise with techniques such as HPLC, GC, MS, NMR, and dissolution
  • Knowledgeable of compendial testing methods (USP/EP) for DS and DP testing
Nice to have
  • Prior experience writing analytical sections in NDA/MAA filings
What the job really is

As the Associate Director of Analytical Development at Kymera, you will lead CMC activities for the clinical development of small-molecule protein degraders. Your role involves developing and validating analytical methods, managing testing activities at contract labs, and ensuring compliance with regulatory standards. You will also collaborate with cross-functional teams to prepare documentation for regulatory submissions and support health authority interactions.

Benefits
  • Competitive compensation package
  • Eligibility for annual bonus
  • Equity participation
  • Comprehensive benefits
Things to weigh
  • No specific mention of remote work options
  • Role involves significant collaboration with external CDMOs
  • The position requires a strong regulatory knowledge base
  • The salary range is broad, indicating potential variability based on experience
Job score4/5
Benefits2/5
Freshness4/5
Career value4/5
Role clarity5/5
Pay transparency5/5

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