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← Flagship Pioneering, Inc.

Senior Scientist, Protein Engineering

Flagship Pioneering, Inc.
Location
Cambridge, MA USA
Posted
12 days ago
Department
Biological Engineering
Salary
$126,000 - $181,500
What they actually want (must-haves)
  • Ph.D. in molecular biology, biochemistry, protein engineering, or a similar field
  • 5+ years of industry or postdoctoral experience
  • Strong track record of scientific and technical innovation in protein variant libraries
  • Deep experience with protein display systems, high-throughput sorting, and sequencing-based readouts
  • Experience with deep mutational scanning or related library-scale mutagenesis methods
  • Hands-on expertise in library-scale molecular cloning and managing library complexity
Nice to have
  • Experience with machine learning methods for protein engineering
  • Experience with statistical analysis of variant fitness landscapes
What the job really is

As a Senior Scientist at FL129, you will play a key role in developing a novel platform technology for small molecule drug discovery. Your responsibilities will include designing and constructing large-scale protein variant libraries, optimizing workflows, and translating experimental data into insights. This hands-on position offers substantial ownership and the opportunity to influence the scientific direction of the company from the outset.

Benefits
  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Weekly lunches
  • Monthly social events
  • Community lunchroom with free snacks and coffee
Things to weigh
  • No specific technologies or tools mentioned, which may affect clarity on the tech stack
  • Role is among the first hires, indicating a startup environment with potential uncertainty
Job score4.4/5
Benefits3/5
Freshness5/5
Career value5/5
Role clarity4/5
Pay transparency5/5

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