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← Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company

Director, Medicinal Chemistry

Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company
Location
Boston, MA
Posted
11 days ago
Department
Discovery Operations
Salary
$150,000.00 to $210,000.00
What they actually want (must-haves)
  • BS/MS in Chemistry; PhD strongly preferred
  • 10+ years designing small molecules as a medicinal chemistry team leader within a biotech and/or pharmaceutical company
  • Expert command of synthetic chemistry and medicinal chemistry principles
  • Solid working knowledge of pharmacology, ADME, pharmaceutical sciences, IP protection, and candidate selection criteria
  • Experience working on CNS targets across all stages of discovery
  • Proven ability to lead and motivate remote and virtual teams
What the job really is

The Director of Medicinal Chemistry will lead a multi-disciplinary team in the drug discovery program focused on CNS GPCRs, particularly for developing small-molecule candidates for sleep-wake disorders. This hands-on leadership role involves managing internal and outsourced chemistry teams, guiding projects from hit-to-lead through IND-ready status, and fostering collaboration across various stakeholders to achieve project goals.

Benefits
  • Annual base salary range of $150,000.00 to $210,000.00
  • Eligible for a discretionary annual bonus
  • Comprehensive benefits package including 401(k) plan
  • Company-sponsored medical, dental, vision, and life insurance
  • Generous paid time off
  • Health and wellness program
Things to weigh
  • Remote-based role with occasional travel
  • Salary range may vary based on qualifications and experience
  • Focus on CNS drug discovery may limit exposure to other therapeutic areas
Job score4.4/5
Benefits3/5
Freshness5/5
Career value4/5
Role clarity5/5
Pay transparency5/5

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