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Senior Director, Clinical Scientist -Neurodegeneration

Arvinas
Location
Remote, Hybrid, New Haven - CT
Posted
10 days ago
Department
Clinical Research
What they actually want (must-haves)
  • 10+ years of relevant pharmaceutical or biotechnology clinical-development experience
  • Demonstrated clinical-development experience in neurodegenerative disease or movement disorders
  • Strong knowledge of ICH-GCP, the drug-development process, study design, statistics, clinical operations, and global regulatory expectations in neurodegenerative disease
  • Working knowledge of longitudinal efficacy endpoints, clinical rating scales, rater variability, disease progression, placebo effects, missing data, and operational challenges in neurodegeneration trials
  • Excellent project leadership, communication, and organizational skills
  • Ability to interpret complex clinical and biomarker data and communicate conclusions, limitations, and recommendations to technical and nontechnical audiences
Nice to have
  • Demonstrated leadership of global early-phase clinical-development studies
  • Experience designing or leading early-phase studies that integrate safety, pharmacokinetics, pharmacodynamics, biomarkers, imaging, dose and regimen selection, and preliminary clinical activity
  • Direct experience with a global PSP or Parkinson’s disease study
  • Experience with relevant neurodegeneration endpoints and assessments
  • Experience with disease-modifying development programs and biomarker strategies
What the job really is

The Senior Director, Clinical Scientist will lead scientific and clinical development activities focused on neurodegenerative diseases, particularly Parkinson's disease and progressive supranuclear palsy (PSP). Responsibilities include developing clinical strategies, designing studies, interpreting data, and collaborating with cross-functional teams. The role requires strong leadership in clinical development and the ability to communicate complex scientific concepts effectively.

Benefits
  • Group medical, vision and dental coverage
  • Group and supplemental life insurance
  • Comprehensive benefits program designed to support health, wellness and financial security
Things to weigh
  • No salary listed
  • Position requires significant experience in clinical development, particularly in neurodegenerative diseases
  • Remote work is available, but candidates must be able to work without visa sponsorship
  • Travel may be required, anticipated at approximately 20%
Job score3.4/5
Benefits2/5
Freshness5/5
Career value5/5
Role clarity5/5
Pay transparency0/5

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