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← Amylyx Pharmaceuticals

Senior Director, Toxicology

Amylyx Pharmaceuticals
Location
Cambridge, MA
Posted
2 months ago
Department
110 - R&D
What they actually want (must-haves)
  • PhD in Toxicology, Pharmacology, Molecular or Cell Biology, or a related science
  • Minimum experience of 10-12 years industry experience in toxicology and nonclinical drug development following completion of PhD or post doc
  • Demonstrated experience developing and executing nonclinical safety strategies to support drug discovery, candidate selection, IND-enabling studies, regulatory submissions, and clinical development
  • Broad knowledge in field of toxicology, with practical knowledge of pharmaceutical toxicology
  • Expert-level knowledge of global preclinical and clinical regulatory guidelines
  • Demonstrated ability to interpret complex toxicology and nonclinical data and translate findings into actionable development strategies
Nice to have
  • DABT certification is desirable
  • Direct experience with targeted delivery approach, rare disease development, endocrine and/or neuromuscular indication is desirable
What the job really is

The Senior Director of Toxicology at Amylyx will lead the development and execution of nonclinical safety programs to support drug candidates from IND-enabling studies to market authorization. This role involves collaborating with cross-functional teams, mentoring scientific talent, and ensuring alignment with regulatory expectations while driving innovative safety assessment strategies. The position requires a strong background in toxicology and the ability to interpret complex data to inform development decisions.

Things to weigh
  • Remote work opportunities available, but not for applicants from certain states (Alaska, Arizona, Hawaii, Michigan, Tennessee)
  • Expected travel to the corporate location in Cambridge, MA several times a year
  • Compensation range provided, but final offer may vary based on experience and qualifications
Job score2.2/5
Benefits1/5
Freshness1/5
Career value4/5
Role clarity5/5
Pay transparency0/5

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